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Corona

Discussion in 'Chit Chat' started by F.W.K., Mar 1, 2020.

  1. bamaman

    bamaman GRCH Dog

    3 players you mentioned sucked !
     
    david63 likes this.
  2. Euro

    Euro Big Dog

    They aren't "better" they are just better paid. Golf players get more money than NBA players and they are nit exactly good as far as athleticism goes.

    MMA is nothing like ball sports, hell its nothing like other fighting sports. You are either a jack of all trades or you are fucked
     
  3. F.W.K.

    F.W.K. CH Dog

    You must see every sport ( just like different dog breeds ) in their own light.
    And yes we'll have our favorite sport and we'll have to respect that.
    Know how hard ( and fun 2 ) it can be to compete on the highest level so hats of to every serious top athlete.
     
  4. F.W.K.

    F.W.K. CH Dog

    BTW to go back to the thread 63 dead 2day.
     
    Soze the killer, oldguy and bamaman like this.
  5. Euro

    Euro Big Dog

    italy had 600 dead in one day, almost 7000 deaths in total
     
  6. bamaman

    bamaman GRCH Dog

    Terrible stuff FWK .I hate it for all that has been impacted by this.Prayers to all.
     
  7. oldguy

    oldguy CH Dog

    Today the British army started building a 4000 bed hospital inside the excel arena in London specifically for coronavirus patients.. This was the London underground this morning.. People not taking self isolation advice seriously and soon be dead because of it!
    tube train.jpg
     
    Soze the killer, david63 and F.W.K. like this.
  8. F.W.K.

    F.W.K. CH Dog

    People who think it is nothing more then a bad flu and don't take it serious deserved a kick in the groin for a reality check.
     
  9. AGK

    AGK Super duper pooper scooper Administrator

  10. Euro

    Euro Big Dog

    spanish flu is "just a flu", didnt stop it from killing 50+ million people tho
     
  11. stickler

    stickler Banned

    Swallow the red pill or the blue pill. Your choice.
    :D
     
  12. bamaman

    bamaman GRCH Dog

    This is is what they call a Novelty Flu which is passed from animal to human.We have no immunity for this .Your body doesnt recognize it and doesnt know to fight it.We have some immunity naturally built in us towards other flu.Its already passed from animal to human amd now its passing from human to human .Some think it could actually go another phase.I think the worse case scenario is if it becomes heat resistant and surviving and spreading in 80 degree plus heat.Maybe someone smarter than me can put it in proper context.
     
    corvettedex and F.D. like this.
  13. Euro

    Euro Big Dog

    we have 4 tyypes of common influenza. A, B, C and D. most common is A which is believed to have mutated from birds and infected humans that way. corona is closest to type C which for the most part aflicts pigs and dogs, having much more severe symptomes.

    Swine influenza virus (SIV) is basically just more mutated strains of A and C influenza. Spanish flu is also theorized to have been another strain that originally only infected swines but started going after people once their immune system would drop
     
    F.D. likes this.
  14. bamaman

    bamaman GRCH Dog

    I was going off memory from what I read but here ya go fella !
    Matt Koci, a professor of immunology, virology, and host-pathogen interactions at North Carolina State University told us by email that while “biology is more complicated than that,” the “lack of no one in the human population having any prior immunity to is a major factor to why this is so much worse than seasonal flu.” Another factor, he told us, is that a few anti-viral drugs have been developed that blunt the impact of some influenza strains, but no such tool exists for the coronavirus.

    Animal-to-Human Mutation in ‘Just Two Weeks’
    The post asserts that mutations in the RNA or DNA of a virus sometimes allow for animal-to-human transfer, but not human-to-human transfer. It then implies a second mutation event is required to allow for human-to-human transfer, and therefore a possible pandemic, to occur:

    Now, here comes this Coronavirus. It existed in animals only, for nobody knows how long. But one day, at an animal market in Wuhan China, in December 2019, it mutated and made the jump from animal to people. At first, only animals could give it to a person. But here is the scary part. In just TWO WEEKS, it mutated again and gained the ability to jump from human to human. Scientists call this quick ability, “slippery”.


    While most viruses mutate multiple times in the process that allows transfer between animal-human and then human-human, “there is no data that I’m aware of that supports the details in this statement,” Koci told us. “We still don’t know what animal it ‘jumped from’ so there is no way to know how long it took before it evolved the ability to move from person-to-person,” he explained. The virus most closely resembles a coronavirus found in bats.

    In fact, this virus may have been pretty much perfectly set up to infect humans right off the bat, so to speak, and therefore would not have required the alleged multiple quick mutations to produce human-to-human transfer. Speaking to Ed Young in The Atlantic, Matthew Friedman of the University of Maryland School of Medicine explained that this novel coronavirus differs from the coronavirus that caused the 2003 SARS outbreak because this one required no modifications to thrive in human cells after its jump from animal to human. Unlike the coronavirus that caused the original SARS, this new one already possessed the ability to recognize a key protein in human cells named ACE2. “It had already found its best way of being a [human] virus,” he told The Atlantic.

    ‘This Virus is Slippery AF’
    The post claims that a quick ability to mutate allowed the virus to mutate “in such a way the way [sic] that it causes great damage to human lungs” and that this fast mutation rate is “why Coronavirus is different from seasonal flu, or H1N1, or any other type of influenza.” The post asserts that the coronavirus, compared to other viruses, mutates unusually fast, i.e. that it is “slippery AF.” This is not true.

    “The virus has been remarkably stable given how much transmission we’ve seen,” Lisa Gralinski, a professor of epidemiology at the University of North Carolina, said in the same Atlantic interview. “That makes sense,” she said, referring to its strong initial ability to infect human cells “because there’s no evolutionary pressure on the virus to transmit better. It’s doing a great job of spreading around the world right now.” David Ho, an epidemiologist at Columbia University’s Aaron Diamond AIDS Research Center, also made this point in a Q and A interview. “This virus is mutating but it has mutated very little so far,” he said.

    “This virus does not seem to mutate any faster than we would expect,” Koci concurred. “It is mutating, all viruses do, and over time, the randomness of these mutations may spit out a new variant that is worse, but current rates of mutations do not seem unusual for these types of viruses.” Mutation rates also do not have anything to do with the damage COVID-19 causes to the lungs in some individuals, according to Ho. “There are differences [in various strains],” he said, “but probably they are functionally not important, so that’s not the explanation for why you see different disease courses among the infected,” he said.

    The Mutation Rate
     
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  15. F.W.K.

    F.W.K. CH Dog

    The blue is the fun pill isn't? LOL
     
    stedz likes this.
  16. Euro

    Euro Big Dog

    And it is not just the virus too. Even if you survive it your immune system and body will be in shambles for a time period. During that you could easily die from secondary infection caused by bacteria
     
    F.D. likes this.
  17. F.D.

    F.D. Top Dog

    stickler likes this.
  18. stedz

    stedz Top Dog

    Terrible news,prince charles has got it now,i wont sleep tonight.
     
  19. AGK

    AGK Super duper pooper scooper Administrator

    Another good write up on how it's different from influenza.

    This is the best explanation I’ve read so far.

    Interesting share about why Corona virus is so different to the flu. And why we shouldn’t assume "I’ll be fine”...
    "From an immunologist at Johns Hopkins University.

    Not really feeling sick and do not want to be..but if you are feeling confused as to why Coronavirus is a bigger deal than Seasonal flu, here it is in a nutshell. I hope this helps. Feel free to share this to others who don’t understand...
    It has to do with RNA sequencing.... I.e. genetics.

    Seasonal flu is an “ALL HUMAN virus”. The DNA/RNA chains that make up the virus are recognized by the human immune system. This means that your body has some immunity to it before it comes around each year... you get immunity two ways...through exposure to a virus, or by getting a flu shot.
    Novel viruses, come from ANIMALS.... the WHO tracks novel viruses in animals, (sometimes for years watching for mutations). Usually these viruses only transfer from animal to animal (pigs in the case of H1N1) (birds in the case of the Spanish flu). But once, one of these animal viruses mutates, and starts to transfer from animals to humans... then it’s a problem, Why? Because we have no natural or acquired immunity.. the RNA sequencing of the genes inside the virus isn’t human, and the human immune system doesn’t recognize it so, we can’t fight it off.

    Now.... sometimes, the mutation only allows transfer from animal to human, for years it’s only transmission is from an infected animal to a human before it finally mutates so that it can now transfer human to human... once that happens..we have a new contagion phase. And depending on the fashion of this new mutation, thats what decides how contagious, or how deadly it’s gonna be..

    H1N1 was deadly....but it did not mutate in a way that was as deadly as the Spanish flu. It’s RNA was slower to mutate and it attacked its host differently, too.

    Fast forward.

    Now, here comes this Coronavirus... it existed in animals only, for nobody knows how long...but one day, at an animal market, in Wuhan China, in December 2019, it mutated and made the jump from animal to people. At first, only animals could give it to a person... But here is the scary part.... in just TWO WEEKS it mutated again and gained the ability to jump from human to human. Scientists call this quick ability, “slippery”

    This Coronavirus, not being in any form a “human” virus (whereas we would all have some natural or acquired immunity). Took off like a rocket. And this was because, Humans have no known immunity...doctors have no known medicines for it.
    And it just so happens that this particular mutated animal virus, changed itself in such a way the way that it causes great damage to human lungs..

    That’s why Coronavirus is different from seasonal flu, or H1N1 or any other type of influenza.... this one is slippery AF. And it’s a lung eater...And, it’s already mutated AGAIN, so that we now have two strains to deal with, strain s, and strain L....which makes it twice as hard to develop a vaccine.

    We really have no tools in our shed, with this. History has shown that fast and immediate closings of public places has helped in the past pandemics.

    Philadelphia and Baltimore were reluctant to close events in 1918 and they were the hardest hit in the US during the Spanish Flu.

    Factoid: Henry VIII stayed in his room and allowed no one near him, till the Black Plague passed...(honestly...I understand him so much better now). Just like us, he had no tools in his shed, except social isolation...
    And let me end by saying....right now it’s hitting older folks harder... but this genome is so slippery...if it mutates again (and it will). Who is to say, what it will do next.

    Be smart folks... acting like you’re immune is so not needed right now.
    #flattenthecurve. Stay home folks... and share this to those that just are not catching on."
     
    Soze the killer, F.W.K. and stedz like this.
  20. oldguy

    oldguy CH Dog

    Sorry Charlie boy.. Covid19 don't give a fck about race, colour, wealth or class! haha!
     
    Soze the killer, kdue, F.W.K. and 2 others like this.

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